2-(Dodecyloxy)ethanol
Based on 1 Customer Validation
2-(Dodecyloxy) ethanol (Ethylene glycol monododecyl ether) is a nonionic ether monohydroxy C12 surfactant with a fragrance-like odor similar to jasmone and gardenia. 2-(Dodecyloxy) ethanol acts as a phase transition inducer and micelle-forming agent. 2-(Dodecyloxy) ethanol also serves as a skin penetration enhancer.
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- Pureté : 98.84%
- CAS No.: 4536-30-5
- Formule: C14H30O2
- Masse moléculaire:230.39
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Stockage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vitro
2-(Dodecyloxy) ethanol (0.16 M; 1 h) enhances the passive transdermal penetration of Ondansetron hydrochloride (HY-B0002) and Diltiazem hydrochloride (HY-14656) through stripped pig skin[3].
2-(Dodecyloxy) ethanol (0.16 M; 1 h) enhances iontophoresis and post-iontophoretic transdermal penetration of ondansetron hydrochloride and diltiazem hydrochloride through stripped porcine skin[3].
2-(Dodecyloxy) ethanol (0.016-160 μM; 24 h) is toxic to cultured human epidermal keratinocytes and reduces the viability of cultured human dermal fibroblasts to approximately 35%[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
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Cell Line:Human epidermal keratinocytes (HEK)
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Concentration:0.016-160 μM
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Incubation Time:24 h
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Result:Was lethal to all HEK at 160 μM.
Did not reduce HEK viability significantly at 16 μM.
Did not cause a significant decrease in HEK viability at concentrations of 1.6 μM or lower.
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Cell Line:Human dermal fibroblasts (HDF)
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Concentration:0.016-160 μM
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Incubation Time:24 h
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Result:Reduced HDF viability to approximately 35% at 160 μM.
Did not cause a significant decrease in HDF viability at concentrations of 16 μM or lower.
Chemical Information
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CAS No. 4536-30-5
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Appearance Liquid (Density: 0.873 g/cm3)
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Masse moléculaire 230.39
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Formule C14H30O2
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Color Colorless to light yellow
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SMILES
OCCOCCCCCCCCCCCC
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Synonyms
Ethylene glycol monododecyl ether
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : ≥ 100 mg/mL (434.05 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.3405 mL | 21.7023 mL | 43.4047 mL | 108.5117 mL |
| 5 mM | 0.8681 mL | 4.3405 mL | 8.6809 mL | 21.7023 mL | |
| 10 mM | 0.4340 mL | 2.1702 mL | 4.3405 mL | 10.8512 mL | |
| 15 mM | 0.2894 mL | 1.4468 mL | 2.8936 mL | 7.2341 mL | |
| 20 mM | 0.2170 mL | 1.0851 mL | 2.1702 mL | 5.4256 mL | |
| 25 mM | 0.1736 mL | 0.8681 mL | 1.7362 mL | 4.3405 mL | |
| 30 mM | 0.1447 mL | 0.7234 mL | 1.4468 mL | 3.6171 mL | |
| 40 mM | 0.1085 mL | 0.5426 mL | 1.0851 mL | 2.7128 mL | |
| 50 mM | 0.0868 mL | 0.4340 mL | 0.8681 mL | 2.1702 mL | |
| 60 mM | 0.0723 mL | 0.3617 mL | 0.7234 mL | 1.8085 mL | |
| 80 mM | 0.0543 mL | 0.2713 mL | 0.5426 mL | 1.3564 mL | |
| 100 mM | 0.0434 mL | 0.2170 mL | 0.4340 mL | 1.0851 mL |
2-(Dodecyloxy)ethanol Related Classifications
HY-W250300 Related Classifications
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