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Cat. No.: HY-P2336

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CCZ01048

4 Cited Publications

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Based on 4 publication(s) in Google Scholar

CCZ01048, a α-melanocyte-stimulating hormone (α-MSH) analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a K_i of 0.31 nM. CCZ01048 shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 is a promising candidate for PET imaging of malignant melanoma.

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Formule: C₇₁H₁₀₅N₂₁O₁₆
Masse moléculaire:1508.72

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CCZ01048 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
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- In Vivo
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Publications (4)
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Activité biologique

Description

Voir tous les produits spécifiques à Isoform Melanocortin Receptor :

In Vivo

The cationic Pip linker to Nle-CycMSHhex, CCZ01048, not only improves tumor uptake, but also generates high tumor-to-normal tissue contrast with PET imaging in a preclinical melanoma model^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Masse moléculaire 1508.72
Formule C₇₁H₁₀₅N₂₁O₁₆
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (4)

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Sci Rep

First-in-human dosimetry and safety evaluation of 68Ga-αMSH derivative for PET imaging of melanoma. [Abstract]

2025 May 22;15(1):17748. PMID: 40404705
Bioconjug Chem

Radiolabeling Optimization and Preclinical Evaluation of the New PSMA Imaging Agent [18F]AlF-P16-093. [Abstract]

2021 May 19;32(5):1017-1026. PMID: 33872489
Appl Radiat Isot

2026 Apr 22.
Iran J Immunol

Letter to the Editor Regarding "An Overview on Serology and Molecular Tests for COVID-19: An Important Challenge of the Current Century (doi: 10.22034/iji.2021.88660.1894.)". [Abstract]

2022 Sep;19(3):337. PMID: 36190387

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (257 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Zhang C, et al. Preclinical Melanoma Imaging with 68Ga-Labeled α-Melanocyte-Stimulating Hormone Derivatives Using PET. Theranostics. 2017;7(4):805-813. Published 2017 Feb 8. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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CCZ01048

4 Cited Publications

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Activité biologique
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CCZ01048

Publications Citing Use of MedChemExpress (MCE) CCZ01048

Voir tous les produits spécifiques à Isoform Melanocortin Receptor

Activité biologique

Chemical Information

Publications (4)

Pureté et documentation

Références

Calculators

Help & FAQs

CCZ01048 Related Classifications

HY-P2336 Related Classifications