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Cat. No.: HY-118244

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Clathrin-IN-3

Clathrin-IN-3 (Compound 25) is a Clathrin inhibitor (IC₅₀: 6.9 μM). Clathrin-IN-3 potenly inhibits clathrin terminal domain-amphiphysin PPI.

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CAS No.: 1419321-16-6
Formule: C₁₉H₁₂KNO₅S
Masse moléculaire:405.47

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Clathrin-IN-3 Chemical Structure

CAS No.: 1419321-16-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Clathrin-IN-3 (Compound 25) is a Clathrin inhibitor (IC₅₀: 6.9 μM). Clathrin-IN-3 potenly inhibits clathrin terminal domain-amphiphysin PPI^[1].

Chemical Information

CAS No. 1419321-16-6
Masse moléculaire 405.47
Formule C₁₉H₁₂KNO₅S
SMILES

O=C(N(C1=O)CC2=CC=CC=C2)C3=C4C1=CC=CC4=CC(S(=O)(O[K])=O)=C3
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. MacGregor KA, et al. Development of 1,8-naphthalimides as clathrin inhibitors. J Med Chem. 2014 Jan 9;57(1):131-43. [Content Brief]

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1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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