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United States

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Cat. No.: HY-W1130442

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DMA4-H228

DMA4-H228 is a highly spleen-targeted, ionizable cationic liposome. DMA4-H228 is used to prepare lipid nanoparticles (LNPs) loaded with mRNA for the delivery of mRNA in vivo.

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CAS No.: 3091917-64-2
Formule: C₅₇H₁₀₆N₄O₁₀
Masse moléculaire:1007.47

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

DMA4-H228 Chemical Structure

CAS No.: 3091917-64-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

DMA4-H228 is a highly spleen-targeted, ionizable cationic liposome. DMA4-H228 is used to prepare lipid nanoparticles (LNPs) loaded with mRNA for the delivery of mRNA in vivo^[1].

Chemical Information

CAS No. 3091917-64-2
Masse moléculaire 1007.47
Formule C₅₇H₁₀₆N₄O₁₀
SMILES

O=C(CCC(N(CCCCCCCC)CCCCCCCC)=O)OCCOC(CCN(CCC1N(CCC1)C)CCC(OCCOC(CCC(N(CCCCCCCC)CCCCCCCC)=O)=O)=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Liang X, et al. Dimethylamino-based synthetic lipidoid nanoparticles for selective mRNA delivery to splenic antigen-presenting cells. J Control Release. 2025 Jun 10;382:113737. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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