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Cat. No.: HY-117285

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Medermycin

(Synonyms: Lactoquinomycin A; LQM-A)

Lactoquinomycin A is a quinone antibiotic. Lactoquinomycin A has the activity of anti-Gram-positive bacteria and some Gram-negative bacteria, but the effect of anti-Gram-negative bacteria is weak and has no effect on fungi. Lactoquinomycin A inhibits a variety of cell lines including lymphoma L5178Y progenitor, Adriamycin resistant, Bleomycin-resistant, human leukemia K562, mouse leukemia L-1210 and mouse leukemia P 388 with ID₅₀ (μg/mL) of 0.02, 0.006, 0.008, 0.033, 0.013 and 0.03, respectively.

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CAS No.: 60227-09-0
Formule: C₂₄H₂₇NO₈
Masse moléculaire:457.47

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Medermycin Chemical Structure

CAS No.: 60227-09-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Voir tous les produits spécifiques à Isoform Antibiotic :

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	0.043 μM Compound: 5	Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay	[PMID: 30209946]
MDA-MB-468	IC₅₀	0.05 μM Compound: 1, lactoquinomycin	Cytotoxicity against human MDA468 cells expressing AKT Cytotoxicity against human MDA468 cells expressing AKT	[PMID: 19309081]
PC-3	IC₅₀	0.015 μM Compound: 5	Cytotoxicity against human PC3 cells after 72 hrs by SRB assay Cytotoxicity against human PC3 cells after 72 hrs by SRB assay	[PMID: 30209946]

Chemical Information

CAS No. 60227-09-0
Masse moléculaire 457.47
Formule C₂₄H₂₇NO₈
SMILES

O=C1C2=C(C(C3=C(O)C([C@H]4C[C@H]([C@@H]([C@H](O4)C)O)N(C)C)=CC=C31)=O)[C@@H](C)O[C@@](C5)([H])[C@]2([H])OC5=O
Synonyms

Lactoquinomycin A; LQM-A
Structure Classification
- Antibiotics
- Other Antibiotics
Initial Source
- Microorganisms
Streptomyces albolongus strain CA-186053
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Beomkoo Chung, et al. Antibacterial Activity and Mode of Action of Lactoquinomycin A from Streptomyces bacillaris. Mar Drugs. 2020 Dec 24;19(1):7. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
Chemical Information
Pureté et documentation
Références

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Medermycin

Voir tous les produits spécifiques à Isoform Antibiotic

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Medermycin Related Classifications

HY-117285 Related Classifications