country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-111026

Copy Link Print Information

PPQ-581

PPQ-581 is an anti-influenza agent with an EC₅₀ of 1 μM for preventing virus-induced cytopathic effects. PPQ-581 inhibits viral protein synthesis. PPQ-581 blocks the RNP nuclear export and cytoplasmic RNP aggregation.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 950381-32-5
Formule: C₂₅H₂₄FN₃O₃
Masse moléculaire:433.47

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

PPQ-581 Chemical Structure

CAS No.: 950381-32-5

Size

Prix

Stock

Quantité

Amount: USD 0.00

* Veuillez sélectionner la quantité avant d'ajouter des articles.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Cellular Effect

Cell Line	Type	Value	Description	References
MDCK	EC₅₀	1 μM Compound: 6a	Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) assessed as virus-mediated cytopathic effect in MDCK cells after 48 to 72 hrs Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) assessed as virus-mediated cytopathic effect in MDCK cells after 48 to 72 hrs	[PMID: 26310893]
MDCK	EC₅₀	1 μM Compound: 6a	Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) expressing nucleoprotein Y52H mutant assessed as virus-mediated cytopathic effect in MDCK cells Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) expressing nucleoprotein Y52H mutant assessed as virus-mediated cytopathic effect in MDCK cells	[PMID: 26310893]
MDCK	EC₅₀	1.4 μM Compound: 6a	Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) expressing nucleoprotein Y289H mutant assessed as virus-mediated cytopathic effect in MDCK cells Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) expressing nucleoprotein Y289H mutant assessed as virus-mediated cytopathic effect in MDCK cells	[PMID: 26310893]
MDCK	EC₅₀	2.3 μM Compound: 6a	Antiviral activity against wild-type Influenza A virus (A/WSN/1933(H1N1)) assessed as virus-mediated cytopathic effect in MDCK cells Antiviral activity against wild-type Influenza A virus (A/WSN/1933(H1N1)) assessed as virus-mediated cytopathic effect in MDCK cells	[PMID: 26310893]
MDCK	EC₅₀	8 μM Compound: 6a	Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) expressing nucleoprotein S377G mutant assessed as virus-mediated cytopathic effect in MDCK cells Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) expressing nucleoprotein S377G mutant assessed as virus-mediated cytopathic effect in MDCK cells	[PMID: 26310893]

Chemical Information

CAS No. 950381-32-5
Masse moléculaire 433.47
Formule C₂₅H₂₄FN₃O₃
SMILES

O=C1C2=C(N3C(C(C4=C(F)C=CC=C4)OCC3(C)C)=C2N(C)C(N1C)=O)C5=CC=CC=C5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Lin MI, et al. Synthesis and inhibitory effects of novel pyrimido-pyrrolo-quinoxalinedione analogues targeting nucleoproteins of influenza A virus H1N1. Eur J Med Chem. 2015 Sep 18;102:477-86. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Obtenir un devis En stock

Other size

Obtenir un devis