q-FTAA
Based on 1 Customer Validation
q-FTAA is an oligothiophene. q-FTAA competes for binding to the X-34 binding site on Aβ fibrils. q-FTAA is applicable to research related to Alzheimer's disease.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 97.06%
- CAS No.: 1352477-22-5
- Formule: C21H14O6S4
- Masse moléculaire:490.59
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Stockage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vitro
q-FTAA (1 μM) competes with 3H-X-34 for binding to recombinant Aβ1-42 fibrils, with an EC50 of 330-630 nM[1].
q-FTAA competes with 3H-X-34 for binding to Aβ deposits (ADPBC) purified from human AD brains, with an EC50 of 300-500 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 1352477-22-5
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Appearance Solid
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Masse moléculaire 490.59
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Formule C21H14O6S4
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Color Yellow to orange
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SMILES
O=C(C1=CC=C(C2=CC(CC(O)=O)=C(C3=CC=C(C4=C(CC(O)=O)C=CS4)S3)S2)S1)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvant et solubilité
In Vitro:
DMSO : 31.25 mg/mL (63.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocole
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Pureté et documentation
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Fiche technique (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.0384 mL | 10.1918 mL | 20.3836 mL | 50.9590 mL |
| 5 mM | 0.4077 mL | 2.0384 mL | 4.0767 mL | 10.1918 mL | |
| 10 mM | 0.2038 mL | 1.0192 mL | 2.0384 mL | 5.0959 mL | |
| 15 mM | 0.1359 mL | 0.6795 mL | 1.3589 mL | 3.3973 mL | |
| 20 mM | 0.1019 mL | 0.5096 mL | 1.0192 mL | 2.5480 mL | |
| 25 mM | 0.0815 mL | 0.4077 mL | 0.8153 mL | 2.0384 mL | |
| 30 mM | 0.0679 mL | 0.3397 mL | 0.6795 mL | 1.6986 mL | |
| 40 mM | 0.0510 mL | 0.2548 mL | 0.5096 mL | 1.2740 mL | |
| 50 mM | 0.0408 mL | 0.2038 mL | 0.4077 mL | 1.0192 mL | |
| 60 mM | 0.0340 mL | 0.1699 mL | 0.3397 mL | 0.8493 mL |
q-FTAA Related Classifications
HY-148547 Related Classifications
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