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Cat. No.: HY-143659

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QW30

QW30 (Compound 19) shows potent antitumor activity with an IC₅₀ value of 0.33 μM.

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CAS No.: 1714112-25-0
Formule: C₂₇H₃₆N₂O₃
Masse moléculaire:436.59

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (240 KB)

QW30 Chemical Structure

CAS No.: 1714112-25-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Protocole (1)
Pureté et documentation
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

QW30 (Compound 19) shows potent antitumor activity with an IC₅₀ value of 0.33 μM.

Cellular Effect

Cell Line	Type	Value	Description	References
DU-145	IC₅₀	0.28 μM Compound: 19; QW30	Antiproliferative activity against human DU145 cells after 96 hrs by SRB assay Antiproliferative activity against human DU145 cells after 96 hrs by SRB assay	[PMID: 27187855]
HCT-116	IC₅₀	0.57 μM Compound: 19; QW30	Antiproliferative activity against human HCT116 cells after 96 hrs by SRB assay Antiproliferative activity against human HCT116 cells after 96 hrs by SRB assay	[PMID: 27187855]
HL-60	IC₅₀	0.04 μM Compound: 19; QW30	Antiproliferative activity against human HL60 cells after 96 hrs by SRB assay Antiproliferative activity against human HL60 cells after 96 hrs by SRB assay	[PMID: 27187855]
HT-29	IC₅₀	0.59 μM Compound: 19; QW30	Antiproliferative activity against human HT-29 cells after 96 hrs by SRB assay Antiproliferative activity against human HT-29 cells after 96 hrs by SRB assay	[PMID: 27187855]
MCF7	IC₅₀	0.28 μM Compound: 19; QW30	Antiproliferative activity against human MCF7 cells after 96 hrs by SRB assay Antiproliferative activity against human MCF7 cells after 96 hrs by SRB assay	[PMID: 27187855]
MDA-MB-231	IC₅₀	0.32 μM Compound: 19; QW30	Antiproliferative activity against human MDA-MB-231 cells after 96 hrs by SRB assay Antiproliferative activity against human MDA-MB-231 cells after 96 hrs by SRB assay	[PMID: 27187855]
PC-3	IC₅₀	0.54 μM Compound: 19; QW30	Antiproliferative activity against human PC3 cells after 96 hrs by SRB assay Antiproliferative activity against human PC3 cells after 96 hrs by SRB assay	[PMID: 27187855]
T47D	EC₅₀	2.56 nM Compound: 19; QW30	Inhibition of colony formation in human T47D cells after 7 days by crystal violet staining based assay Inhibition of colony formation in human T47D cells after 7 days by crystal violet staining based assay	[PMID: 27187855]
T47D	EC₅₀	6.42 μM Compound: 19; QW30	Antimigratory activity in human T47D cells assessed as inhibition of cell migration after 12 hrs by crystal violet staining based transwell migration assay Antimigratory activity in human T47D cells assessed as inhibition of cell migration after 12 hrs by crystal violet staining based transwell migration assay	[PMID: 27187855]
T47D	IC₅₀	0.01 μM Compound: 19; QW30	Antiproliferative activity against human T47D cells after 96 hrs by SRB assay Antiproliferative activity against human T47D cells after 96 hrs by SRB assay	[PMID: 27187855]

Chemical Information

CAS No. 1714112-25-0
Masse moléculaire 436.59
Formule C₂₇H₃₆N₂O₃
SMILES

CC1(C)[C@@H](O)CC[C@]2(C)C3=C(C=C(C(NC4=CC=C(N(C)C)C=C4)=O)C(OC)=C3)CC[C@@]12[H]
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocole

All Animals and Diseases

Subcutaneous Cell-Line-Derived Xenograft
Subcutaneous cell-line-derived xenograft (CDX) models are established by implanting cultured human cancer cell lines into immunodeficient mice, where the injected cells form localized tumors that can be monitored in vivo as a measure of tumorigenic potential, growth kinetics, and treatment response. These models are widely used in oncology research because they allow reproducible tumor formation and enable comparative assessment of tumor growth between different cell lines or genetic manipulations in a controlled in vivo microenvironment. Subcutaneous implantation of cancer cells in immunodeficient mice is a standard approach for evaluating tumor growth behavior and therapeutic response across multiple cancer types, including prostate, esophageal, pancreatic, and colon cancer models.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (240 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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