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Cat. No.: HY-P10924

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Roseltide rT1

Roseltide rT1 is a neutrophil elastase inhibitor (IC₅₀=0.47 μM) rich in cysteine and one of the Roseltide (rT1-rT8) family members. Roseltide rT1 improves cAMP accumulation stimulated by neutrophil elastase in vitro, showing potential for inhibiting related diseases.

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CAS No.: 2206692-95-5
Formule: C₁₁₀H₁₇₇N₃₁O₃₁S₆
Masse moléculaire:2622.16

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Roseltide rT1 Chemical Structure

CAS No.: 2206692-95-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Chemical Information

CAS No. 2206692-95-5
Masse moléculaire 2622.16
Formule C₁₁₀H₁₇₇N₃₁O₃₁S₆
Sequence

Cys-Ile-Pro-Arg-Gly-Gly-Ile-Cys-Leu-Val-Ala-Leu-Ser-Gly-Cys-Cys-Asn-Ser-Pro-Gly-Cys-Ile-Phe-Gly-Ile-Cys-Ala (Disulfide bridge: Cys1-Cys16, Cys8-Cys21, Cys15-Cys26)
Sequence Shortening

CIPRGGICLVALSGCCNSPGCIFGICA (Disulfide bridge: Cys1-Cys16, Cys8-Cys21, Cys15-Cys26)
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocole

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (258 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Loo S, et al. Identification and Characterization of Roseltide, a Knottin-type Neutrophil Elastase Inhibitor Derived from Hibiscus sabdariffa. Sci Rep. 2016 Dec 19;6:39401. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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