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Cat. No.: HY-122645

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SMARCA2-IN-4

SMARCA2-IN-4 (Compound 26) is an inhibitor for SWI/SNF chromatin remodeling complexe SMARCA by targeting the bromodomains. SMARCA2-IN-4 exhibits high affinity for PB1(5), SMARCA2B and SMARCA4 with K_d of 124, 262 and 417 nM.

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CAS No.: 1915012-19-9
Formule: C₁₇H₁₉ClN₄O
Masse moléculaire:330.81

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

SMARCA2-IN-4 Chemical Structure

CAS No.: 1915012-19-9

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

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Chemical Information

CAS No. 1915012-19-9
Masse moléculaire 330.81
Formule C₁₇H₁₉ClN₄O
SMILES

CN(CC1)CCN1/C=C2CCN(C\2=N3)C4=CC=CC(Cl)=C4C3=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Sutherell CL, et al., Identification and Development of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting Complex. J Med Chem. 2016 May 26;59(10):5095-101. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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SMARCA2-IN-4

Voir tous les produits spécifiques à Isoform SWI/SNF Complex

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

SMARCA2-IN-4 Related Classifications

HY-122645 Related Classifications