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Cat. No.: HY-181016

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CX3CR1-IN-2

CX3CR1-IN-2 (Compound 77) is a CX3CR1 inhibitor with an IC₅₀ of 0.04 μM. CX3CR1-IN-2 can block the interaction between CX3CR1 and its ligand fractalkine (CX3CL1). CX3CR1-IN-2 can be used for research of cardiovascular disease, such as heart failure and cardiomyopathy .

For research use only. We do not sell to patients.

CAS No.: 3105688-14-7
Formula: C₁₉H₂₄F₃N₅O₄S₂
Molecular Weight:507.55

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

CX3CR1-IN-2 Chemical Structure

CAS No.: 3105688-14-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 3105688-14-7
Molecular Weight 507.55
Formula C₁₉H₂₄F₃N₅O₄S₂
SMILES

FC(F)(F)C(C=CC=C1)=C1C(CSC2=NC(NS(C)(=O)=O)=NC(N[C@@H](CO)CC(C)C)=N2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sabnis RW. Novel Compounds as NLRP3 Inhibitors for Treating Cardiovascular Diseases. ACS Med Chem Lett. 2024 Jul 11;15(8):1184-1185. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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