1. Immunology/Inflammation
  2. CX3CR1
  3. CX3CR1-IN-2

CX3CR1-IN-2 (Compound 77) is a CX3CR1 inhibitor with an IC50 of 0.04 μM. CX3CR1-IN-2 can block the interaction between CX3CR1 and its ligand fractalkine (CX3CL1). CX3CR1-IN-2 can be used for research of cardiovascular disease, such as heart failure and cardiomyopathy .

For research use only. We do not sell to patients.

CX3CR1-IN-2

CX3CR1-IN-2 Chemical Structure

CAS No. : 3105688-14-7

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Description

CX3CR1-IN-2 (Compound 77) is a CX3CR1 inhibitor with an IC50 of 0.04 μM. CX3CR1-IN-2 can block the interaction between CX3CR1 and its ligand fractalkine (CX3CL1). CX3CR1-IN-2 can be used for research of cardiovascular disease, such as heart failure and cardiomyopathy [1].

Molecular Weight

507.55

Formula

C19H24F3N5O4S2

CAS No.
SMILES

FC(F)(F)C(C=CC=C1)=C1C(CSC2=NC(NS(C)(=O)=O)=NC(N[C@@H](CO)CC(C)C)=N2)=O

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
CX3CR1-IN-2
Cat. No.:
HY-181016
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