Cy3 Dextran (MW 20000)
Based on 1 Customer Validation
Cy3 Dextran (MW 20000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm).
For research use only. We do not sell to patients.
- Molecular Weight:20000 (Average)
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Due to its macromolecular properties and stable fluorescence, Cy3 Dextran (MW 20,000) is mainly used to study the permeability of biological barriers and the transport and metabolic processes of macromolecules, for example, in assessing vascular and tissue permeability, investigating cellular uptake and endocytosis, and tracing drug carriers and materials.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 20000 (Average)
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Color Purple to purplish red
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SMILES
O=C(NCCNC([Cyanine 3])=O)COC[C@H]1C[C@@H](OC)[C@H](O)[C@@H](O[C@H]2[C@H](O)C(OC)[C@H](O)[C@@H](CO)C2)[C@@H]1O.[n]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Brock R, et al. Fluorescence correlation microscopy of cells in the presence of autofluorescence. Biophys J. 1998 Nov;75(5):2547-57. [Content Brief]
[2]. Poon W, et al. Elimination Pathways of Nanoparticles. ACS Nano. 2019;13(5):5785-5798. [Content Brief]
[3]. Anfray A, et al. A cell-autonomous role for border-associated macrophages in ApoE4 neurovascular dysfunction and susceptibility to white matter injury. Nat Neurosci. 2024;27(11):2138-2151. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)