DBCO-PEG24-Maleimide
Based on 1 Customer Validation
DBCO-PEG24-Maleimide is a bioconjugation reagent. DBCO-PEG24-Maleimide contains a DBCO group, a maleimide group, and a PEG segment with 24 repeating units. DBCO-PEG24-Maleimide mediates strain-promoted azide-alkyne cycloaddition and maleimide-thiol conjugation reactions, thereby conjugating SpCas9 variants to DN1S and IPP2 protein domains.
For research use only. We do not sell to patients.
- Purity: 97.00%
- CAS No.: 2924872-84-2
- Formula: C76H122N4O29
- Molecular Weight:1555.81
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Biological Activity
DBCO-PEG24-Maleimide can be conjugated with DN1S, and the resulting conjugate undergoes partial conjugation with F688AzF SpCas9 at room temperature for 3 days[1].
DBCO-PEG24-Maleimide binds to IPP2, and the resulting complex binds to F688AzF SpCas9 at room temperature[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2924872-84-2
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Appearance Oil
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Molecular Weight 1555.81
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Formula C76H122N4O29
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Color Colorless to light yellow
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SMILES
O=C1C=CC(=O)N1CCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)NCCC(=O)N2C=3C=CC=CC3C#CC=4C=CC=CC4C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)