Laninamivir TFA
Based on 8 publication(s) in Google Scholar
Laninamivir TFA (R 125489 TFA) is an antiviral compound with inhibitory and prophylactic activity against influenza A and B viruses. Laninamivir TFA is a long-acting neuraminidase inhibitor administered by nasal inhalation. Laninamivir TFA has shown good safety and efficacy in the inhibition of influenza viruses.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 203120-18-7
- Formel: C15H23F3N4O9
- Molecular Weight:460.36
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Publications Citing Use of MedChemExpress (MCE) Laninamivir TFA
More- Nat Commun. 2025 Jul 1;16(1):5831. [Abstract]
- NPJ Digit Med. 2025 Nov 21;8(1):712. [Abstract]
- PLoS Pathog. 2026 Jan 23;22(1):e1013863. [Abstract]
- Sci Rep. 2021 Aug 11;11(1):16293. [Abstract]
- Int J Infect Dis. 2024 Sep:146:107134. [Abstract]
- Microbiol Spectr. 2026 Feb 18:e0332825. [Abstract]
- Viruses. 2024 Sep 14;16(9):1467. [Abstract]
- PLoS One. 2018 Jul 12;13(7):e0200761. [Abstract]
Biologische Aktivität
Chemical Information
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CAS. Nr. 203120-18-7
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Molecular Weight 460.36
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Formel C15H23F3N4O9
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SMILES
OC[C@@H](O)[C@H]([C@@]1([H])[C@@H]([C@H](C=C(C(O)=O)O1)NC(N)=N)NC(C)=O)OC.OC(C(F)(F)F)=O
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Synonyms
R 125489 TFA
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (8)
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Journal Impact Factor
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Most Recent
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Nat Commun
Single-domain antibodies directed against hemagglutinin and neuraminidase protect against influenza B viruses. [Abstract]2025 Jul 1;16(1):5831. PMID: 40593518 -
NPJ Digit Med
Predictive modeling & mechanistic validation of synergistic pimodivir combinations for anti-influenza therapy via PB2cap affinity boost. [Abstract]2025 Nov 21;8(1):712. PMID: 41272280 -
PLoS Pathog
Intra-patient neuraminidase mutations in avian H5N1 influenza virus reduce sialidase activity to complement weaker hemagglutinin binding and facilitate human infection. [Abstract]2026 Jan 23;22(1):e1013863. PMID: 41575943 -
Sci Rep
Substitution of I222L-E119V in neuraminidase from highly pathogenic avian influenza H7N9 virus exhibited synergistic resistance effect to oseltamivir in mice. [Abstract]2021 Aug 11;11(1):16293. PMID: 34381119 -
Int J Infect Dis
Antiviral susceptibility of SARS-CoV-2 and influenza viruses from 3 co-infected pediatric patients. [Abstract]2024 Sep:146:107134. PMID: 38944411 -
Microbiol Spectr
Neuraminidase of influenza A viruses induces global desialylation of host cells via its intracellular function. [Abstract]2026 Feb 18:e0332825. PMID: 41705853 -
Viruses
The Synergistic Effect of Baloxavir and Neuraminidase Inhibitors against Influenza Viruses In Vitro. [Abstract]2024 Sep 14;16(9):1467. PMID: 39339943 -
PLoS One
An easy, rapid, and sensitive method for detection of drug-resistant influenza virus by using a sialidase fluorescent imaging probe, BTP3-Neu5Ac. [Abstract]2018 Jul 12;13(7):e0200761. PMID: 30001430
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Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Laninamivir TFA Related Classifications
HY-14818B Related Classifications
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