Nitisinone-13C6
Nitisinone-13C6 is a 13C-labeled Nitisinone (HY-B0607). Nitisinone is an orally active, competitive and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with an IC50 of 173 nM. Nitisinone promotes tyrosine accumulation in a dose-dependent manner. nitisinone can be used in studies of hereditary tyrosinemia type 1 (HT-1) (a rare genetic disorder) and albinism.
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- CAS. Nr.: 1246815-63-3
- Formel: C813C6H10F3NO5
- Molecular Weight:335.18
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Biologische Aktivität
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1246815-63-3
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Unlabeled Cas 104206-65-7
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Molecular Weight 335.18
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Formel C813C6H10F3NO5
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SMILES
O=C([13CH]1[13C]([13CH2][13CH2][13CH2][13C]1=O)=O)C2=C(C=C(C=C2)C(F)(F)F)[N+]([O-])=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Nitisinone-13C6 Related Classifications
HY-W777526 Related Classifications
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