Nonane-1,9-dithiol
Based on 1 Customer Validation
Nonane-1,9-dithiol is a PROTAC linker that can be used in the synthesis of PROTACs.
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- Reinheit : 98.47%
- CAS. Nr.: 3489-28-9
- Formel: C9H20S2
- Molecular Weight:192.38
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Speicherung:
RT, stored under nitrogen.
In solvent -80°C, 1 year , -20°C, 6 months
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
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Help & FAQs
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Biologische Aktivität
Beschreibung
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E769 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 3489-28-9
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Appearance Liquid
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Molecular Weight 192.38
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Formel C9H20S2
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SMILES
SCCCCCCCCCS
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
RT, stored under nitrogen
In solvent -80°C 1 year -20°C 6 months
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (519.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Reinheit & Dokumentation
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Data Sheet (239 KB)
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SDS (453 KB)
- English - EN (453 KB)
- Français - FR (453 KB)
- Deutsch - DE (453 KB)
- Norwegian - NO (453 KB)
- Español - ES (453 KB)
- Swedish - SV (453 KB)
- Italian - IT (453 KB)
- Korean - KR (453 KB)
- Portuguese - PT (453 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 5.1980 mL | 25.9902 mL | 51.9805 mL | 129.9511 mL |
| 5 mM | 1.0396 mL | 5.1980 mL | 10.3961 mL | 25.9902 mL | |
| 10 mM | 0.5198 mL | 2.5990 mL | 5.1980 mL | 12.9951 mL | |
| 15 mM | 0.3465 mL | 1.7327 mL | 3.4654 mL | 8.6634 mL | |
| 20 mM | 0.2599 mL | 1.2995 mL | 2.5990 mL | 6.4976 mL | |
| 25 mM | 0.2079 mL | 1.0396 mL | 2.0792 mL | 5.1980 mL | |
| 30 mM | 0.1733 mL | 0.8663 mL | 1.7327 mL | 4.3317 mL | |
| 40 mM | 0.1300 mL | 0.6498 mL | 1.2995 mL | 3.2488 mL | |
| 50 mM | 0.1040 mL | 0.5198 mL | 1.0396 mL | 2.5990 mL | |
| 60 mM | 0.0866 mL | 0.4332 mL | 0.8663 mL | 2.1659 mL | |
| 80 mM | 0.0650 mL | 0.3249 mL | 0.6498 mL | 1.6244 mL | |
| 100 mM | 0.0520 mL | 0.2599 mL | 0.5198 mL | 1.2995 mL |
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