PB038
Based on 1 Customer Validation
PB038 is a Drug-liker containing a PEG unit and a cleavable linker attached to Exatecan.
For research use only. We do not sell to patients.
- Purity: 98.99%
- CAS No.: 2851058-71-2
- Formula: C98H149FN12O36
- Molecular Weight:2090.29
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2851058-71-2
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Appearance Solid
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Molecular Weight 2090.29
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Formula C98H149FN12O36
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Color Off-white to yellow
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SMILES
O=C(N1CCCCCC(N[C@H](C(N[C@H](C(N[C@H](C(NC2=CC=C(COC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@]7(CC)O)=C(C6=O)COC7=O)=NC8=CC(F)=C(C(CC3)=C84)C)=O)C=C2)=O)CCCNC(N)=O)=O)C(C)C)=O)CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN(C[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)C[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)=O)=O)C=CC1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (47.84 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (281 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.4784 mL | 2.3920 mL | 4.7840 mL | 11.9601 mL |
| 5 mM | 0.0957 mL | 0.4784 mL | 0.9568 mL | 2.3920 mL | |
| 10 mM | 0.0478 mL | 0.2392 mL | 0.4784 mL | 1.1960 mL | |
| 15 mM | 0.0319 mL | 0.1595 mL | 0.3189 mL | 0.7973 mL | |
| 20 mM | 0.0239 mL | 0.1196 mL | 0.2392 mL | 0.5980 mL | |
| 25 mM | 0.0191 mL | 0.0957 mL | 0.1914 mL | 0.4784 mL | |
| 30 mM | 0.0159 mL | 0.0797 mL | 0.1595 mL | 0.3987 mL | |
| 40 mM | 0.0120 mL | 0.0598 mL | 0.1196 mL | 0.2990 mL |