Desamino lenalidomide-acetylene-C2-NH2 TFA
Based on 1 Customer Validation
Desamino lenalidomide-acetylene-C2-NH2 TFA is an E3 ligand-linker conjugate that incorporates a ligand based on CRBN and a linker, and can be used for the synthesis of PROTAC.
For research use only. We do not sell to patients.
- CAS No.: 3065251-37-5
- Formula: C19H18F3N3O5
- Molecular Weight:425.36
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Chemical Information
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CAS No. 3065251-37-5
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Appearance Solid
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Molecular Weight 425.36
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Formula C19H18F3N3O5
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SMILES
O=C1NC(C(CC1)N2C(C3=C(C2)C(C#CCCN)=CC=C3)=O)=O.OC(C(F)(F)F)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 25 mg/mL (58.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (248 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3509 mL | 11.7547 mL | 23.5095 mL | 58.7737 mL |
| 5 mM | 0.4702 mL | 2.3509 mL | 4.7019 mL | 11.7547 mL | |
| 10 mM | 0.2351 mL | 1.1755 mL | 2.3509 mL | 5.8774 mL | |
| 15 mM | 0.1567 mL | 0.7836 mL | 1.5673 mL | 3.9182 mL | |
| 20 mM | 0.1175 mL | 0.5877 mL | 1.1755 mL | 2.9387 mL | |
| 25 mM | 0.0940 mL | 0.4702 mL | 0.9404 mL | 2.3509 mL | |
| 30 mM | 0.0784 mL | 0.3918 mL | 0.7836 mL | 1.9591 mL | |
| 40 mM | 0.0588 mL | 0.2939 mL | 0.5877 mL | 1.4693 mL | |
| 50 mM | 0.0470 mL | 0.2351 mL | 0.4702 mL | 1.1755 mL |