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Cat. No.: HY-185904

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Desthiobiotin-FP

Desthiobiotin-FP is a covalent activity-based probe used for labeling, detecting and enriching active serine hydrolases in complex protein samples. Desthiobiotin-FP combines a fluorophosphonate (FP) reactive group with a desthiobiotin tag for affinity pull-down. Desthiobiotin-FP enables activity profiling of serine- and cysteine-based enzymes.

For research use only. We do not sell to patients.

CAS No.: 1811556-65-6
Formula: C₂₂H₄₃FN₃O₄P
Molecular Weight:463.57

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Desthiobiotin-FP Chemical Structure

CAS No.: 1811556-65-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Bioz

Biological Activity

Description

In Vitro

Desthiobiotin-FP (2 μM; 90 min) labels 18 serine and cysteine enzymes involved in lipid metabolism and cell wall biosynthesis in Mycobacterium tuberculosis mc²6230 lysates^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1811556-65-6
Molecular Weight 463.57
Formula C₂₂H₄₃FN₃O₄P
SMILES

CCOP(CCCCCCCCCCNC(CCCCC[C@H]1NC(N[C@H]1C)=O)=O)(F)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Nguyen PC, et al. Oxadiazolone derivatives, new promising multi-target inhibitors against M. tuberculosis. Bioorganic chemistry. 2018 Dec;81:414-424. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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