DMG-PEG2000-Mal-Cys-penetratin
Based on 1 Customer Validation
DMG-PEG2000-Mal-Cys-penetratin is a conjugate composed of dimyristoylglycerol (DMG), a PEG chain, and terminal maleimide (Mal). DMG-PEG2000-Mal-Cys-penetratin combines the membrane compatibility of lipids, the specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers) by maleimide, and cell-penetrating peptides, making it suitable for research on biomaterial construction and drug delivery to cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 95.0%
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保管条件:
-80°C
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
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Help & FAQs
生物活性
製品説明
体外実験
The structure of DMG-PEG2000-Mal-Cys-penetratin comprises four key components, which work synergistically:
DMG: As a hydrophobic anchor, it is responsible for firmly embedding the entire molecule into the membrane structure of lipid nanoparticles.
PEG chain: As a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing non-specific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
Maleimide: Located at the end of the PEG chain, it acts as a reaction interface, undergoing specific Michael addition reactions with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers) to achieve targeting or tracking functions.
Cys-penetratin: Efficiently helps the entire nanoparticle cross the cell membrane and enter the cell to exert its effects.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
化学情報
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性状 Oil
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Color Yellow to brown
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SMILES
CCCCCCCCCCCCCC(OC(COCCOCCNC(CCN1C(CC(SC[C@@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCSC)C(N[C@@H](CCCCN)C(N[C@@H](CC5=CNC6=CC=CC=C56)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)N)C1=O)=O)=O)COC(CCCCCCCCCCCCC)=O)=O.[n]
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輸送条件
Shipping with dry ice.
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保管条件
-80°C
純度とドキュメンテーション
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データシート (241 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
DMG-PEG2000-Mal-Cys-penetratin 関連分類
HY-186175 関連分類
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