DNA-PK-IN-10
DNA-PK-IN-10 is a DNA-PK inhibitor. DNA-PK-IN-10 can be used for the research of breast cancer and non-small cell lung cancer.
For research use only. We do not sell to patients.
- CAS No.: 2919315-89-0
- Formula: C25H28N6O2
- Molecular Weight:444.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
DNA-PK-IN-10 (Example 31) inhibits the viability of MDA-MB-468 cells, with an IC50 of 11.2 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2919315-89-0
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Molecular Weight 444.53
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Formula C25H28N6O2
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SMILES
O=C(N1C)N(C2CCC(NCCOC3=CC=NC4=C5)CC2)C(C1=CN6)=CC6=NC(C=C43)=C5C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Breast Cancer Modeling
Breast cancer is a heterogeneous cancer, and it has been distinguished into four subtypes: luminal A, luminal B, HER2-positive and basal-like. Molecular mutations, epigenetic alterations, hormone exposure and immune microenvironment are related to the progression of breast cancer.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DNA-PK-IN-10 Related Classifications
HY-153943 Related Classifications
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