2. Neuronal Signaling GPCR/G Protein
  3. Serotonin Transporter 5-HT Receptor
  4. DSP-1053 benzenesulfonate

DSP-1053, a benzylpiperidine derivative, is a potent serotonin transporter (SERT) inhibitor with a Ki of 1.02 nM. DSP-1053 shows partial 5-HT1A receptor agonistic activity with a Ki of 5.05 nM. DSP-1053 has antidepressant activity.

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DSP-1053 benzenesulfonate Chemical Structure

DSP-1053 benzenesulfonate Chemical Structure

CAS No. : 1176326-78-5

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DSP-1053 benzenesulfonate Related Antibodies

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Description

DSP-1053, a benzylpiperidine derivative, is a potent serotonin transporter (SERT) inhibitor with a Ki of 1.02 nM. DSP-1053 shows partial 5-HT1A receptor agonistic activity with a Ki of 5.05 nM. DSP-1053 has antidepressant activity[1].

IC50 & Target[1]

5-HT1A Receptor

5.05 nM (Ki)

Clinical Trial
Molecular Weight

660.62

Formula

C32H38BrNO7S
CAS No.
SMILES

O=C1CCOC2=CC=C(CCN3CCC(CC4=CC=C(Br)C(OCCOC)=C4)CC3)C=C12.O=S(C5=CC=CC=C5)(O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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DSP-1053 benzenesulfonate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DSP-10531176326-78-5DSP1053DSP 1053Serotonin Transporter5-HT Receptor5-HTTSERTSLC6A4Serotonin Receptor5-hydroxytryptamine ReceptorBenzylpiperidine,?Serotonin Transporter5-HT1AantidepressantInhibitorinhibitorinhibit

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