E3 Ligase Ligand-linker Conjugate 237
E3 Ligase Ligand-linker Conjugate 237 (Compound 43) is a CRBN ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 237 is used for the synthesis of the IRAK4 PROTAC degrader KT-474 (HY-145483).
For research use only. We do not sell to patients.
- Formula: C26H32N4O6
- Molecular Weight:496.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Description
IC50 & Target
[1]|
Cereblon |
Chemical Information
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Molecular Weight 496.56
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Formula C26H32N4O6
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SMILES
O=C1N(C(CCC2=O)C(N2)=O)C3=CC=CC(C#CCOC4CCN(C(OC(C)(C)C)=O)CC4)=C3N1C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)