1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugate
  3. Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH

Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH (Synonyms: Cereblon Ligand-Linker Conjugates 14; E3 ligase Ligand-Linker Conjugates 49)

Cat. No.: HY-128848 Purity: 95.02%
Handling Instructions

Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

For research use only. We do not sell to patients.

Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH Chemical Structure

Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH Chemical Structure

CAS No. : 2351103-63-2

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100 mg USD 480 In-stock
Estimated Time of Arrival: December 31
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Description

Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

IC50 & Target

Cereblon

 

Molecular Weight

648.70

Formula

C₃₁H₄₄N₄O₁₁

CAS No.
SMILES

O=C(NC1=O)CCC1N(C2=O)C(C3=C2C(NCCNC(COCCCCCOCCOCCCCCOCC(O)=O)=O)=CC=C3)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 55 mg/mL (84.78 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5415 mL 7.7077 mL 15.4154 mL
5 mM 0.3083 mL 1.5415 mL 3.0831 mL
10 mM 0.1542 mL 0.7708 mL 1.5415 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

Keywords:

Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOHCereblon Ligand-Linker Conjugates 14 E3 ligase Ligand-Linker Conjugates 49E3 Ligase Ligand-Linker ConjugateInhibitorinhibitorinhibit

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Product Name:
Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH
Cat. No.:
HY-128848
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