1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugate
  3. E3 ligase Ligand-Linker Conjugates 49

E3 ligase Ligand-Linker Conjugates 49 

Cat. No.: HY-128848
Handling Instructions

E3 ligase Ligand-Linker Conjugates 49 incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 49 can be used to design PROTAC degrader.

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E3 ligase Ligand-Linker Conjugates 49 Chemical Structure

E3 ligase Ligand-Linker Conjugates 49 Chemical Structure

CAS No. : 2351103-63-2

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Description

E3 ligase Ligand-Linker Conjugates 49 incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 49 can be used to design PROTAC degrader.

IC50 & Target

Cereblon

 

Molecular Weight

648.70

Formula

C₃₁H₄₄N₄O₁₁

CAS No.

2351103-63-2

SMILES

O=C(NC1=O)CCC1N(C2=O)C(C3=C2C(NCCNC(COCCCCCOCCOCCCCCOCC(O)=O)=O)=CC=C3)=O

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
E3 ligase Ligand-Linker Conjugates 49
Cat. No.:
HY-128848
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