2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. EGFR-IN-68

EGFR-IN-68 (Compound 8d) is a potent EGFR inhibitor with an IC50 of 0.33 μM. EGFR-IN-68 shows anticancer activity.

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EGFR-IN-68

EGFR-IN-68 Chemische Struktur

CAS. Nr. : 2416925-03-4

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EGFR-IN-68 Related Antibodies

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Beschreibung

EGFR-IN-68 (Compound 8d) is a potent EGFR inhibitor with an IC50 of 0.33 μM. EGFR-IN-68 shows anticancer activity[1].

In Vitro

EGFR-IN-68 (Compound 8d) shows cytotoxicity with IC50 values of 3.79 ± 0.04 μM and 25.56 ± 1.59 μM against MCF-7 and WI-38, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

EGFR-IN-68 Related Antibodies
Molekulargewicht

354.44

Formel

C24H22N2O
CAS. Nr.
SMILES

COC1=CC=C(N2N=C(C3=CC=CC=C3)CC2/C=C/C4=CC=CC=C4)C=C1
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Room temperature in continental US; may vary elsewhere.
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EGFR-IN-68 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EGFR-IN-682416925-03-4EGFREpidermal growth factor receptorErbB-1HER1breast cancerMCF-7anticancerInhibitorinhibitorinhibit

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