ENL/AF9 YEATS-IN-1
ENL/AF9 YEATS-IN-1 is a ENL/AF9 YEATS domain inhibitor. ENL/AF9 YEATS-IN-1 suppresses oncogene expression in cells by inhibiting the ENL/AF9 YEATS domain. ENL/AF9 YEATS-IN-1 can be used in leukemia research.
For research use only. We do not sell to patients.
- CAS No.: 2657651-10-8
- Formula: C23H26N6O
- Molecular Weight:402.49
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MV4-11 | IC50 |
61 nM
|
Exhibits potent antiproliferative activity in MV4-11 (MLL-AF4 acute myeloid leukemia) cells.
Exhibits potent antiproliferative activity in MV4-11 (MLL-AF4 acute myeloid leukemia) cells.
|
en |
ENL/AF9 YEATS-IN-1 (Example 6) effectively inhibits the binding of the ENL YEATS domain to the crotonylated histone H3K9cr peptide, with an IC50 of 0.133 μM[1].
ENL/AF9 YEATS-IN-1 (12 days) exhibits potent antiproliferative activity in MV4-11 (MLL-AF4 acute myeloid leukemia) cells, with an IC50 of 61 nM following 12 consecutive days of treatment[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2657651-10-8
-
Molecular Weight 402.49
-
Formula C23H26N6O
-
SMILES
O=C(C1=CC=C(N(N=C2C)C)C2=C1)NC3=NC=C(C(N4)=C3)C=C4CN5CCC[C@@H]5C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ENL/AF9 YEATS-IN-1 Related Classifications
HY-188074 Related Classifications
Powered by Bioz