EP3 antagonist 5
EP3 antagonist 5 (Compound 22) is an EP3 receptor antagonist with an IC50 value of 67 nM.
For research use only. We do not sell to patients.
- CAS No.: 499147-44-3
- Formula: C29H32FNO4
- Molecular Weight:477.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 67 nM (EP3)[1].
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
67 nM
Compound: 22
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Antagonist activity at mouse EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase intracellular calcium level in presence of 1% BSA by fluorimetry
Antagonist activity at mouse EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase intracellular calcium level in presence of 1% BSA by fluorimetry
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[PMID: 20129791] |
Chemical Information
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CAS No. 499147-44-3
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Molecular Weight 477.57
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Formula C29H32FNO4
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SMILES
O=C(O)CCC1=CC=C(C=C1C(NC(C2=CC=C(C(F)=C2)C)CC(C)C)=O)COC3=CC=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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