ERα ligand 4
ERα ligand 4 is a ligand of ERα and can be used for the synthesis of PROTACs, such as NEP168 (HY-180959).
For research use only. We do not sell to patients.
- CAS No.: 97818-93-4
- Formula: C24H22O3
- Molecular Weight:358.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
ERα |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | EC50 |
300 nM
Compound: 15 (Y=H)
|
Stimulation of MCF-7 cell proliferation
Stimulation of MCF-7 cell proliferation
|
[PMID: 8941399] |
| MCF7 | IC50 |
320 nM
Compound: 15 (Y=H)
|
Effect on estradiol-stimulated MCF-7 cell proliferation
Effect on estradiol-stimulated MCF-7 cell proliferation
|
[PMID: 8941399] |
Chemical Information
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CAS No. 97818-93-4
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Molecular Weight 358.43
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Formula C24H22O3
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SMILES
OC(COC1=CC=C(/C(C2=CC=CC=C2)=C(CC)\C3=CC=CC=C3)C=C1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)