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Cat. No.: HY-12814R

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TH588 (Standard)

TH588 (Standard) is the analytical standard of TH588. This product is intended for research and analytical applications. TH588 is first-in-class nudix hydrolase family inhibitor that potently and selectively engage and inhibit the MTH1 (IC50= 5 nM).

For research use only. We do not sell to patients.

CAS No.: 1609960-31-7
Formula: C₁₃H₁₂Cl₂N₄
Molecular Weight:295.17

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

TH588 (Standard) Chemical Structure

CAS No.: 1609960-31-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Chemical Information
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Bioz

Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1609960-31-7
Molecular Weight 295.17
Formula C₁₃H₁₂Cl₂N₄
SMILES

NC1=NC(C2=CC=CC(Cl)=C2Cl)=CC(NC3CC3)=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Gad H, et al. MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool. Nature. 2014 Apr 10;508(7495):215-21. [Content Brief]

Calculators

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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