4-Fluorobenzaldehyde
Based on 1 Customer Validation
4-Fluorobenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 97.28%
- No. CAS: 459-57-4
- Fòrmula: C7H5FO
- Peso molecular:124.11
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Almacenamiento:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| B16-F10 | IC50 |
70.74 μM
Compound: 15-7
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Cytotoxicity against mouse B16F10 cells assessed as reduction in cell viability
Cytotoxicity against mouse B16F10 cells assessed as reduction in cell viability
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[PMID: 30594028] |
Chemical Information
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No. CAS 459-57-4
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Appearance <-10°C Solid,>-10°C Liquid
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Peso molecular 124.11
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Fòrmula C7H5FO
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Color Colorless to light yellow
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SMILES
O=CC1=CC=C(F)C=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvente y solubilidad
DMSO : 100 mg/mL (805.74 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (20.14 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (20.14 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Pureza y Documentación
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Ficha de datos (242 KB)
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SDS (748 KB)
- English - EN (748 KB)
- Français - FR (748 KB)
- Deutsch - DE (748 KB)
- Norwegian - NO (748 KB)
- Español - ES (748 KB)
- Swedish - SV (748 KB)
- Italian - IT (748 KB)
- Korean - KR (748 KB)
- Portuguese - PT (748 KB)
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Instrucciones de manejo (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 8.0574 mL | 40.2868 mL | 80.5737 mL | 201.4342 mL |
| 5 mM | 1.6115 mL | 8.0574 mL | 16.1147 mL | 40.2868 mL | |
| 10 mM | 0.8057 mL | 4.0287 mL | 8.0574 mL | 20.1434 mL | |
| 15 mM | 0.5372 mL | 2.6858 mL | 5.3716 mL | 13.4289 mL | |
| 20 mM | 0.4029 mL | 2.0143 mL | 4.0287 mL | 10.0717 mL | |
| 25 mM | 0.3223 mL | 1.6115 mL | 3.2229 mL | 8.0574 mL | |
| 30 mM | 0.2686 mL | 1.3429 mL | 2.6858 mL | 6.7145 mL | |
| 40 mM | 0.2014 mL | 1.0072 mL | 2.0143 mL | 5.0359 mL | |
| 50 mM | 0.1611 mL | 0.8057 mL | 1.6115 mL | 4.0287 mL | |
| 60 mM | 0.1343 mL | 0.6714 mL | 1.3429 mL | 3.3572 mL | |
| 80 mM | 0.1007 mL | 0.5036 mL | 1.0072 mL | 2.5179 mL | |
| 100 mM | 0.0806 mL | 0.4029 mL | 0.8057 mL | 2.0143 mL |