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Referencia número: HY-146059

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Antibacterial agent 99

Antibacterial agent 99 (compound 7b) is a potent antibacterial agent. Antibacterial agent 99 shows significant antibacterial and antifungal activity. Antibacterial agent 99 dose not show haemolytic activity.

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No. CAS: 2452306-13-5
Fòrmula: C₂₇H₂₇BrN₂
Peso molecular:459.42

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Antibacterial agent 99 Chemical Structure

No. CAS: 2452306-13-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Actividad biológica

Descripciòn

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	CC₅₀	2.1 μg/mL Compound: 7b	Cytotoxicity against HEK293 cells measured after 20 hrs by resazurin dye based fluorescence assay Cytotoxicity against HEK293 cells measured after 20 hrs by resazurin dye based fluorescence assay	[PMID: 32619924]

In Vitro

Antibacterial agent 99 (compound 7b) shows antimicrobial activity with MIC of 8, 8, 16 μg/mL for Sa - Staphylococcus aureus (MRSA) ATCC 43300, Ca - Candida albicansATCC 90028, Cn - Cryptococcus neoformans H99 ATCC 208821, respectively^[1].
Antibacterial agent 99 shows cytotoxicity with an CC₅₀ of 2.1 μg/mL for HEK293 cells, and haemolytic activity with an HC₁₀ of >32 μg/mL for human red blood cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 2452306-13-5
Peso molecular 459.42
Fòrmula C₂₇H₂₇BrN₂
SMILES

CC1=CC=C(C=C1)[N+]2=C3N(CCCCC3)C(C4=CC=C(C=C4)C5=CC=CC=C5)=C2.[Br-]
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Demchenko S, et al. Synthesis, antibacterial and antifungal activity of new 3-biphenyl-3H-Imidazo[1,2-a]azepin-1-ium bromides. Eur J Med Chem. 2020 Sep 1;201:112477. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Antibacterial agent 99

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Antibacterial agent 99

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Antibacterial agent 99 Related Classifications

HY-146059 Related Classifications