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United States

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Cat. No.: HY-169383

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FA4-Cu

FA4-Cu is a complex of the potent pancreatic cancer inhibitor FA4 and Cu(II) that induces apoptosis via ER and mitochondrial stress.

For research use only. We do not sell to patients.

Formula: C₂₇H₃₃Cl₂CuN₅O₂S
Molecular Weight:626.10

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

FA4-Cu Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

FA4-Cu is a complex of the potent pancreatic cancer inhibitor FA4 and Cu(II) that induces apoptosis via ER and mitochondrial stress^[1].

Chemical Information

Molecular Weight 626.10
Formula C₂₇H₃₃Cl₂CuN₅O₂S
SMILES

CN(C1=N[N]2=C(C3=O[Cu]2(S1)Cl)C4=CC=CC=C4N3CCCCN5CCC6(CC5)C7=C(CO6)C=CC=C7)C.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Barbanente A, et al. First-In-Class Thiosemicarbazone Metal Complexes Targeting the Sigma-2 Receptor (S2R) as an Innovative Strategy against Pancreatic Cancer. J Med Chem. 2024 Nov 28;67(22):20118-20134. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Minimum order quantity

100 mg

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