FAK/Aurora kinase-IN-1
FAK/Aurora kinase-IN-1 is a FAK and aurora kinase inhibitor with IC50 values of 6.61 nM and 0.91 nM, respectively. FAK/Aurora kinase-IN-1 shows anticancer effects (WO2018019252A1; compound 11).
For research use only. We do not sell to patients.
- CAS No.: 2178117-69-4
- Formula: C23H24ClN7O3
- Molecular Weight:481.93
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Aurora Kinase Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 2178117-69-4
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Molecular Weight 481.93
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Formula C23H24ClN7O3
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SMILES
ClC1=C(NC2=C(C(C(N(C)C)=O)=O)C=CC=C2)N=C(N=C1)NC3=CN=C(C=C3)N4CCOCC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)