Fmoc-aminooxy-PFP ester
Based on 1 Customer Validation
Fmoc-aminooxy-PFP ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- CAS No.: 2752177-95-8
- Formula: C23H14F5NO5
- Molecular Weight:479.35
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2752177-95-8
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Appearance Solid
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Molecular Weight 479.35
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Formula C23H14F5NO5
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Color White to off-white
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SMILES
O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NOCC(OC4=C(F)C(F)=C(F)C(F)=C4F)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (208.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0862 mL | 10.4308 mL | 20.8616 mL | 52.1540 mL |
| 5 mM | 0.4172 mL | 2.0862 mL | 4.1723 mL | 10.4308 mL | |
| 10 mM | 0.2086 mL | 1.0431 mL | 2.0862 mL | 5.2154 mL | |
| 15 mM | 0.1391 mL | 0.6954 mL | 1.3908 mL | 3.4769 mL | |
| 20 mM | 0.1043 mL | 0.5215 mL | 1.0431 mL | 2.6077 mL | |
| 25 mM | 0.0834 mL | 0.4172 mL | 0.8345 mL | 2.0862 mL | |
| 30 mM | 0.0695 mL | 0.3477 mL | 0.6954 mL | 1.7385 mL | |
| 40 mM | 0.0522 mL | 0.2608 mL | 0.5215 mL | 1.3038 mL | |
| 50 mM | 0.0417 mL | 0.2086 mL | 0.4172 mL | 1.0431 mL | |
| 60 mM | 0.0348 mL | 0.1738 mL | 0.3477 mL | 0.8692 mL | |
| 80 mM | 0.0261 mL | 0.1304 mL | 0.2608 mL | 0.6519 mL | |
| 100 mM | 0.0209 mL | 0.1043 mL | 0.2086 mL | 0.5215 mL |
Fmoc-aminooxy-PFP ester Related Classifications
HY-133404 Related Classifications
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