Fmoc-Val-Ala-PAB-PNP
Based on 1 Customer Validation
Fmoc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.28%
- CAS 番号: 1394238-92-6
- 分子式: C37H36N4O9
- 分子量:680.70
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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HY-126353
Fmoc-Val-Ala-PAB-OHADC linker -
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Val-cit-PAB-OHADC Linker -
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Mc-Val-Cit-PABC-PNPADC Linker -
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Exatecan mesylateTopoisomerase I Inhibitor -
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Fmoc-Val-Cit-PABADC Linker -
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AZD3965MCT1 Inhibitor -
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STM2457METTL3 Inhibitor -
HY-10087
NavitoclaxBcl-2 Inhibitor -
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MC-Val-Cit-PABADC Linker -
HY-135975
MC-Val-Ala-PAB-PNPADC Linker -
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Alloc-Val-Ala-pABADC Linker -
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Fmoc-Val-Cit-PAB-PNPADC Linker
生物活性
製品説明
IC50 & Target
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Protease Cleavable Linker |
Cleavable Linker |
体外実験
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
化学情報
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CAS 番号 1394238-92-6
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性状 Solid
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分子量 680.70
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分子式 C37H36N4O9
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Color White to light yellow
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SMILES
[O-][N+](C(C=C1)=CC=C1OC(OCC(C=C2)=CC=C2NC([C@H](C)NC([C@H](C(C)C)NC(OCC3C4=CC=CC=C4C5=CC=CC=C53)=O)=O)=O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (146.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4691 mL | 7.3454 mL | 14.6908 mL | 36.7269 mL |
| 5 mM | 0.2938 mL | 1.4691 mL | 2.9382 mL | 7.3454 mL | |
| 10 mM | 0.1469 mL | 0.7345 mL | 1.4691 mL | 3.6727 mL | |
| 15 mM | 0.0979 mL | 0.4897 mL | 0.9794 mL | 2.4485 mL | |
| 20 mM | 0.0735 mL | 0.3673 mL | 0.7345 mL | 1.8363 mL | |
| 25 mM | 0.0588 mL | 0.2938 mL | 0.5876 mL | 1.4691 mL | |
| 30 mM | 0.0490 mL | 0.2448 mL | 0.4897 mL | 1.2242 mL | |
| 40 mM | 0.0367 mL | 0.1836 mL | 0.3673 mL | 0.9182 mL | |
| 50 mM | 0.0294 mL | 0.1469 mL | 0.2938 mL | 0.7345 mL | |
| 60 mM | 0.0245 mL | 0.1224 mL | 0.2448 mL | 0.6121 mL | |
| 80 mM | 0.0184 mL | 0.0918 mL | 0.1836 mL | 0.4591 mL | |
| 100 mM | 0.0147 mL | 0.0735 mL | 0.1469 mL | 0.3673 mL |
Fmoc-Val-Ala-PAB-PNP 関連分類
HY-136136 関連分類
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