Fosciclopirox (Standard)
Fosciclopirox (Standard) is the analytical standard of Fosciclopirox (HY-109174). This product is intended for research and analytical applications. Fosciclopirox (CPX-POM) suppresses growth of urothelial cancer by targeting the γ-secretase complex. Fosciclopirox selectively delivers the active metabolite, Ciclopirox (CPX), to the entire urinary tract. Ciclopirox has anticancer activity in a number of solid and hematologic malignancies.
For research use only. We do not sell to patients.
- CAS No.: 1380539-06-9
- Formula: C13H20NO6P
- Molecular Weight:317.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1380539-06-9
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Molecular Weight 317.27
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Formula C13H20NO6P
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SMILES
O=C1C=C(C)C=C(C2CCCCC2)N1OCOP(O)(O)=O
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Synonyms
CPX-POM (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Weir SJ, et al. Fosciclopirox suppresses growth of high-grade urothelial cancer by targeting the γ-secretase complex. Cell Death Dis. 2021 May 31;12(6):562. [Content Brief]
[2]. Weir SJ, Wood R, Schorno K, Brinker AE, Ramamoorthy P, Heppert K, Rajewski L, Tanol M, Ham T, McKenna MJ, McCulloch W, Dalton M, Reed GA, Jensen RA, Baltezor MJ, Anant S, Taylor JA 3rd. Preclinical Pharmacokinetics of Fosciclopirox, a Novel Treatment of Urothelial Cancers, in Rats and Dogs. J Pharmacol Exp Ther. 2019 Aug;370(2):148-159. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)