PLpro-IN-3
PLpro-IN-3 (compound 26R) is a potent Papain-like protease (PLpro) inhibitor with a IC50 of 1.0μM. PLpro-IN-3 exhibits antiviral activity against SARS-CoV-2 with a EC50 of 4.3 μM.
For research use only. We do not sell to patients.
- CAS No.: 3047093-72-8
- Formula: C29H24FN3O3S
- Molecular Weight:513.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Vero C1008 | CC50 |
124.2 μM
Compound: 26r
|
Cytotoxicity against african green monkey Vero E6 cells incubated for 48 hrs
Cytotoxicity against african green monkey Vero E6 cells incubated for 48 hrs
|
[PMID: 38871484] |
Chemical Information
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CAS No. 3047093-72-8
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Molecular Weight 513.58
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Formula C29H24FN3O3S
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SMILES
O=C(C1=CC=C(CNC2=CC(C3=NOC(C(C4=CC=C(C5=CC=CC=C5)C(F)=C4)C)=N3)=CC=C2C)S1)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)