Neridronate (Standard)
Neridronate (Standard) is the analytical standard of Neridronate (HY-119443). This product is intended for research and analytical applications. Neridronate is an aminobisphosphonate. Neridronate induces osteoblast differentiation, enhances alkaline phosphatase activity and mineralized nodule formation. Neridronate inhibits endothelial cell proliferation, fibroblast growth factor-2-induced capillary-like tube formation, and angiogenesis. Neridronate can be used for osteogenesis imperfecta and Paget’s disease of bone.
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- CAS No.: 79778-41-9
- Formule: C6H17NO7P2
- Masse moléculaire:277.15
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 79778-41-9
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Masse moléculaire 277.15
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Formule C6H17NO7P2
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SMILES
OC(P(O)(O)=O)(CCCCCN)P(O)(O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Gatti D, et al. Clinical development of neridronate: potential for new applications. Ther Clin Risk Manag. 2013;9:139-47. [Content Brief]
[2]. Frediani B, et al. Long-term effects of neridronate on human osteoblastic cell cultures. Bone. 2004;35(4):859-869. [Content Brief]
[3]. Ribatti D, et al. Neridronate inhibits angiogenesis in vitro and in vivo. Clin Rheumatol. 2007;26(7):1094-1098. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)