IR-820
Based on 2 publication(s) in Google Scholar
IR-820 (New Indocyanine Green) is an infrared blood pool contrast agent. IR-820 also is normally used as a laser and near-infrared dye to detect and quantify diseased tissue in live animals.
For research use only. We do not sell to patients.
- Purity : 95.83%
- CAS No.: 172616-80-7
- Formula: C46H50ClN2NaO6S2
- Molecular Weight:849.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) IR-820
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Biological Activity
Description
In Vitro
Guide (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).
In vivo[1]:
1. The powdered IR-820 was freshly mixed with phosphate buffer saline (PBS) to a final concentration of 0.2 mM and 100 μl of this solution was used for injecting into experimental animals.
2. Used 2 groups of four Hairless SKHi/sKHl mice. The first group was injected by intravenous tail vein injection while the second was injected intraperitoneally.
3. IR-820 has maximal excitation and emission wavelengths of 710 nm and 820 nm, respectively. Both groups were serially imaged for 8 days.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Emission (Em)
820
Excitation (Ex)
800
Chemical Information
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CAS No. 172616-80-7
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Appearance Solid
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Molecular Weight 849.47
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Formula C46H50ClN2NaO6S2
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Color Brown to black
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SMILES
CC1(C(C2=CC=CC=C2C=C3)=C3[N+](CCCC[S](=O)([O-])=O)=C1/C=C/C(CCC/C4=C\C=C(C5(C)C)/N(C6=C5C7=CC=CC=C7C=C6)CCCC[S](=O)(O[Na])=O)=C4Cl)C
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Synonyms
New Indocyanine Green
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Mater Today Bio
"Top-down and Bottom-up" cholesterol-depleting biomimetic nanoparticle for enhancing sonodynamic therapy against hepatocellular carcinoma. [Abstract]2025 Sep 30:35:102370. PMID: 41104047 -
Int J Nanomedicine
IR-820@NBs Combined with MG-132 Enhances the Anti-Hepatocellular Carcinoma Effect of Sonodynamic Therapy. [Abstract]2023 Nov 1:18:6199-6212. PMID: 37933299
Solvent & Solubility
In Vitro:
DMSO : 5 mg/mL (5.89 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (280 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1772 mL | 5.8860 mL | 11.7720 mL | 29.4301 mL |
| 5 mM | 0.2354 mL | 1.1772 mL | 2.3544 mL | 5.8860 mL |