Acetylaranotin
Acetylaranotin is a metabolite produced by the fungus Arachniotus aureus, exhibiting antitumor activity. Acetylaranotin is utilized in research within the field of oncology for its potential in anti-cancer applications.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 20485-01-2
- Fòrmula: C22H20N2O8S2
- Peso molecular:504.53
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
Chemical Information
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No. CAS 20485-01-2
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Peso molecular 504.53
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Fòrmula C22H20N2O8S2
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SMILES
O=C1[C@@]2(CC3=COC=C[C@H](OC(C)=O)[C@@H]3N2C4=O)SS[C@@]4(C5)N1[C@@H]6C5=COC=C[C@@H]6OC(C)=O
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Subcutaneous Cell-Line-Derived Xenograft
Subcutaneous cell-line-derived xenograft (CDX) models are established by implanting cultured human cancer cell lines into immunodeficient mice, where the injected cells form localized tumors that can be monitored in vivo as a measure of tumorigenic potential, growth kinetics, and treatment response. These models are widely used in oncology research because they allow reproducible tumor formation and enable comparative assessment of tumor growth between different cell lines or genetic manipulations in a controlled in vivo microenvironment. Subcutaneous implantation of cancer cells in immunodeficient mice is a standard approach for evaluating tumor growth behavior and therapeutic response across multiple cancer types, including prostate, esophageal, pancreatic, and colon cancer models.
Pureza y Documentación
Referencias
[1]. Nagarajan R, et al. Aranotin and related metabolites from Arachniotus aureus. I. Determination of structure[J]. Journal of the American Chemical Society, 1968, 90(11): 2980-2982. [Content Brief]
[2]. Shindelman J, et al. Atelopidtoxin from the Panamanian frog, Atelopus zeteki[J]. Toxicon, 1969, 7(4): 315-319. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)