AM580 (Standard)
AM580 (Standard) is the analytical standard of AM580. This product is intended for research and analytical applications. AM580 is a selective RARα agonist with IC50 and EC50 of 8 nM and 0.36 nM, respectively.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98%
- No. CAS: 102121-60-8
- Fòrmula: C22H25NO3
- Peso molecular:351.44
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureza y Documentación
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Help & FAQs
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HY-10475
AM580RARα Agonist -
HY-10475G
AM580 (GMP)RARα Agonist -
HY-14171
BexaroteneRXR Agonist -
HY-B0107
AcitretinAutophagy Inducer -
HY-14799
PalovaroteneRARγ Agonist -
HY-15373
FenretinideAutophagy Inducer -
HY-14649
Retinoic acidRAR Agonist -
HY-15682
TTNPBApoptosis Inducer -
HY-14652
TamibaroteneApoptosis Inducer -
HY-W004500
All-trans-retinalVitamin A Metabolite -
HY-14649R
Retinoic acid (Standard) -
HY-14649G
Retinoic acid (GMP)RAR Agonist
Product Information
Information
Aplicación
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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No. CAS 102121-60-8
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Peso molecular 351.44
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Fòrmula C22H25NO3
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SMILES
CC(CC1)(C)C2=C(C=CC(C(NC3=CC=C(C(O)=O)C=C3)=O)=C2)C1(C)C
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Synonyms
CD336 (Standard); NSC608001 (Standard); Ro 40-6055 (Standard)
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Gianní M, et al. AM580, a stable benzoic derivative of retinoic acid, has powerful and selective cyto-differentiating effects on acute promyelocytic leukemia cells. Blood. 1996 Feb 15;87(4):1520-31. [Content Brief]
[2]. Lu Y, et al. Mechanism of inhibition of MMTV-neu and MMTV-wnt1 induced mammary oncogenesis by RARalpha agonist AM580. Oncogene. 2010 Jun 24;29(25):3665-76. [Content Brief]
[3]. Bosch A, et al. Reversal by RARα agonist Am580 of c-Myc-induced imbalance in RARα/RARγ expression during MMTV-Myc tumorigenesis. Breast Cancer Res. 2012 Aug 24;14(4):R121. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AM580 (Standard) Related Classifications
HY-10475R Related Classifications
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