cMCoFx1
cMCoFx1 is a potent and selective FXIIa cyclic peptide inhibitor. cMCoFx1 has high binding affinity (KD: 900 pM) and inhibitory activity (Ki: 370 pM) for FXIIa. cMCoFx1 can effectively inhibit endogenous clotting pathways, and cMCoFx1 is stable in serum and non-cytotoxic.
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- No. CAS: 2853605-24-8
- Fòrmula: C146H232N52O44S6
- Peso molecular:3612.12
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
Ki: 370 pM (FXIIa)[1]
Chemical Information
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No. CAS 2853605-24-8
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Peso molecular 3612.12
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Fòrmula C146H232N52O44S6
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Sequence
cyclo(Asp-Gly-Gly-Ile-Cys-Pro-Arg-Ile-Gly-Arg-Leu-Cys-Arg-Arg-Asp-Ser-Asp-Cys-Pro-Gly-Ala-Cys-Ile-Cys-Arg-Ala-Thr-Arg-Phe-Cys-Gly-Ser-Gly-Tyr) (disulfide bridge: Cys2-Cys19; Cys4-Cys26; Cys10-Cys32)
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Sequence Shortening
cyclo(ACICRATRFCGSGYDGGICPRIGRLCRRDSDCPG) (disulfide bridge: Cys2-Cys19; Cys4-Cys26; Cys10-Cys32)
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
cMCoFx1 Related Classifications
HY-P10860 Related Classifications
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