CMDA
CMDA is a prodrug that can release cytotoxic molecules under the action of CPG2. CMDA can be used for cancer research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 122665-73-0
- Fòrmula: C17H23ClN2O8S
- Peso molecular:450.89
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| LoVo | IC50 |
>500 μM
Compound: 1
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Inhibitory concentration was evaluated against colorectal tumar cell line LoVo
Inhibitory concentration was evaluated against colorectal tumar cell line LoVo
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[PMID: 8676345] |
| LS174T | IC50 |
>800200 μM
Compound: 40
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Compound was evaluated for its cytotoxicity without carboxypeptidase G2 in the colorectal cell line LS174T for 1 hour
Compound was evaluated for its cytotoxicity without carboxypeptidase G2 in the colorectal cell line LS174T for 1 hour
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[PMID: 8057284] |
| LS174T | IC50 |
200 μM
Compound: 40
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Compound was evaluated for its cytotoxicity with carboxypeptidase G2 in the colorectal cell line LS174T for 1 hour
Compound was evaluated for its cytotoxicity with carboxypeptidase G2 in the colorectal cell line LS174T for 1 hour
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[PMID: 8057284] |
| WiDr | IC50 |
100 μM
Compound: CMDA
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Compound was tested for cytotoxicity in WiDr cells engineered for stable expression of surface-tethered CPG2
Compound was tested for cytotoxicity in WiDr cells engineered for stable expression of surface-tethered CPG2
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[PMID: 12699387] |
| WiDr | IC50 |
3230 μM
Compound: CMDA
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Compound was tested for cytotoxicity in WiDr cells engineered for stable expression of beta-galactosidase
Compound was tested for cytotoxicity in WiDr cells engineered for stable expression of beta-galactosidase
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[PMID: 12699387] |
Chemical Information
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No. CAS 122665-73-0
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Peso molecular 450.89
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Fòrmula C17H23ClN2O8S
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SMILES
CS(OCCN(C1=CC=C(C(N[C@H](C(O)=O)CCC(O)=O)=O)C=C1)CCCl)(=O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CMDA Related Classifications
HY-106650 Related Classifications
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