Curvulol
Curvulol is an antimicrobial agent with a polyketide structure. Curvulol can be isolated from Taxus baccata ( Chaetosphaeronema achilleae). Curvulol has a significant cytotoxicity against L929 and KB-3-1 cells, and strongly inhibits Staphylococcus aureus biofilm formation with a MIC of 64 μg/mL.
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- No. CAS: 15817-76-2
- Fòrmula: C10H12O4
- Peso molecular:196.20
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Curvulol (Compound 7) shows an antimicrobial activity against Rhodoturula glutinis DSM 10134, Schizosaccharomyces pombe DSM 70572, Staphylococcus aureus DSM 346 and Bacillus subtilis DSM 10 with a MIC of 33.33 μg/mL[1].
Curvulol has a significant cytotoxicity with IC50 s of 5.5 and 7.5 μg/mL for L929 and KB-3-1 cells, respectively[1].
Curvulol (4-256 μg/mL) strongly inhibits Staphylococcus aureus biofilm formation of 96.18% at 256 μg/mL, and with a MIC of 64 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 15817-76-2
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Peso molecular 196.20
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Fòrmula C10H12O4
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SMILES
OC1=C2C(CO[C@H]2C)=CC(OC)=C1O
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Structure Classification
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Initial Source
Chaetosphaeronema achilleae
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)