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Referencia número: HY-182278

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Flubeneteram

Flubeneteram is a succinate dehydrogenase inhibitor with an IC₅₀ of 0.0484 μM. Flubeneteram disrupts succinate dehydrogenase activity. Flubeneteram demonstrates protective effects against Rhizoctonia solani and Sphaerotheca fuliginea in preclinical models. Flubeneteram can be used for research related to fungal infections.

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No. CAS: 1676101-39-5
Fòrmula: C₁₉H₁₃ClF₅N₃O₂
Peso molecular:445.77

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Flubeneteram Chemical Structure

No. CAS: 1676101-39-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- In Vitro
Chemical Information
Protocolo (1)
Pureza y Documentación
Referencias
Calculators
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Actividad biológica

Descripciòn

In Vitro

Flubeneteram (0.01-50 μM) potently inhibits succinate dehydrogenase in a in vitro cell-free assay with an IC₅₀ of 0.0484 μM^[1].
Flubeneteram (0.75-200 mg/L) exhibits 100% control of both rice sheath blight (caused by Rhizoctonia solani) and cucumber powdery mildew (caused by Sphaerotheca fuliginea) at concentrations of 200, 100, and 50 mg/L, with potent activity maintained at lower concentrations against rice sheath blight^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.

Chemical Information

No. CAS 1676101-39-5
Peso molecular 445.77
Fòrmula C₁₉H₁₃ClF₅N₃O₂
SMILES

O=C(C1=CN(C)N=C1C(F)F)NC2=C(OC3=CC=C(C(F)(F)F)C=C3Cl)C=CC=C2
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocolo

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Yang G F,et al.Pyrazole amide compound containing diphenyl ether, and application and pesticide composition of pyrazole amide compound. CN104557709A. 2015-04-29.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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