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Referencia número: HY-148969

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FPPS-IN-1

FPPS-IN-1 is a potent non-bisphosphonate Farnesyl pyrophosphate synthase (FPPS) inhibitor with an IC₅₀ 0.2 μM. FPPS-IN-1 can be used for the research of cancers.

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No. CAS: 1250273-31-4
Fòrmula: C₁₅H₁₁NO₄
Peso molecular:269.26

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

FPPS-IN-1 Chemical Structure

No. CAS: 1250273-31-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

FPPS-IN-1 is a potent non-bisphosphonate Farnesyl pyrophosphate synthase (FPPS) inhibitor with an IC₅₀ 0.2 μM. FPPS-IN-1 can be used for the research of cancers^[1].

In Vitro

FPPS-IN-1 (compound 11) has low trans-cellular permeability, medium-to-low Caco-2 permeability, and no measurable bone affinity^[1].
FPPS-IN-1 (30 μM) shows no hERG channel inhibition^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 1250273-31-4
Peso molecular 269.26
Fòrmula C₁₅H₁₁NO₄
SMILES

O=C(O)C1=CC=2C=CC=3C=CC=CC3C2N1CC(=O)O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Jahnke W, et al. Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat Chem Biol. 2010;6(9):660-666. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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