FPPS-IN-1
FPPS-IN-1 is a potent non-bisphosphonate Farnesyl pyrophosphate synthase (FPPS) inhibitor with an IC50 0.2 μM. FPPS-IN-1 can be used for the research of cancers.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1250273-31-4
- Fòrmula: C15H11NO4
- Peso molecular:269.26
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
In Vitro
FPPS-IN-1 (compound 11) has low trans-cellular permeability, medium-to-low Caco-2 permeability, and no measurable bone affinity[1].
FPPS-IN-1 (30 μM) shows no hERG channel inhibition[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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No. CAS 1250273-31-4
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Peso molecular 269.26
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Fòrmula C15H11NO4
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SMILES
O=C(O)C1=CC=2C=CC=3C=CC=CC3C2N1CC(=O)O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)