FPPS-IN-2
FPPS-IN-2 (compound 4a) is a potent and orally active HFPPS inhibitor with an IC50 value of 1.108 µM. FPPS-IN-2 has the potential for the research of osteoporosis.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C24H26O6
- Peso molecular:410.46
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
IC50: 1.108 µM (HFPPS)[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:200-250 g, Female Wistar rats[1]
-
Dosage:0.1, 1, 10 mg/kg
-
Administration:P.o.; daily for 8 weeks
-
Result:Increased the osteocalcin level only with the 1, and 10 mg/kg doses, reduced urinary calcium.
Chemical Information
-
Peso molecular 410.46
-
Fòrmula C24H26O6
-
SMILES
COC1=CC(/C=C/C(C)=O)=CC=C1OCCOC2=CC=C(/C=C/C(C)=O)C=C2OC
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)