KRP-109
KRP-109 is a neutrophil elastase (NE) inhibitor with activity in reducing lung inflammation. KRP-109 improves survival in mouse models and reduces the number of neutrophils and inflammation in the alveolar walls. KRP-109 significantly reduced cell and neutrophil counts in bronchoalveolar lavage fluid, as well as cytokine levels such as interleukin 1β and macrophage inflammatory protein 2. KRP-109 can be used in the research of severe pneumonia.
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- No. CAS: 1275996-50-3
- Fòrmula: C26H30N4O7
- Peso molecular:510.54
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Chemical Information
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No. CAS 1275996-50-3
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Peso molecular 510.54
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Fòrmula C26H30N4O7
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SMILES
OC(/C=C\C(O)=O)=O.CCC1=C2C(N=C(C3=C(N4C[C@H](CC4)N(C)C)N=CC=C3)OC2=O)=CC(OC)=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
KRP-109 Related Classifications
HY-11046A Related Classifications
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