PSB-22269
PSB-22269 is a GPR17 antagonist with a Ki value of 8.91 nM. PSB-22269 further demonstrated significant inhibitory effects in cAMP and G protein activation assays. Molecular docking studies revealed that the binding site of PSB-22269 contains positively charged arginine residues and a hydrophobic pocket. PSB-22269 provides a strategy to promote remyelination and holds promise for research in the field of multiple sclerosis.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C26H21NO6
- Peso molecular:443.45
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Chemical Information
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Peso molecular 443.45
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Fòrmula C26H21NO6
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SMILES
COC1=CC(C(O)=O)=C(NC(C2=CC=C(C3=C(C4=CC=CC(OC)=C4)C=CC=C3)O2)=O)C=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PSB-22269 Related Classifications
HY-159920 Related Classifications
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