SCH 54388
SCH 54388 is an orally active metabolite of Felbamate (HY-B0184). SCH 54388 significantly attenuates the functional impairment effects induced by Scopolamine (HY-N0296) or Dizocilpine (HY-15084B). SCH 54388 can be used in research related to cognitive impairment.
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- No. CAS: 25451-53-0
- Fòrmula: C10H13NO3
- Peso molecular:195.22
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
SCH 54388 (0.01-0.1 mg/kg; s.c.; single administration) reverses dizocilpine-induced cognitive impairment in CF-1 mice[1].
SCH 54388 (10-100 mg/kg; s.c.; single administration) produces statistically significant analgesic effects in CF-1 mice[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Charles River BALB (male, 25-30 g, scopolamine-induced cognitive impairment)[1]
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Dosage:0.1 mg/kg; 1.0 mg/kg; 10 mg/kg
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Administration:s.c.; single dose
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Result:Produced mean reentry latencies statistically greater than scopolamine alone.
Demonstrated a statistically significant overall treatment effect.
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Animal Model:Charles River BALB (male, 25-30 g, scopolamine-induced cognitive impairment)[1]
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Dosage:0.1 mg/kg; 1.0 mg/kg; 10 mg/kg
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Administration:p.o.; single dose
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Result:Produced mean reentry latencies statistically greater than scopolamine alone.
Demonstrated a statistically significant overall treatment effect.
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Animal Model:Charles River CF-1 (male, 25-30 g, dizocilpine-induced cognitive impairment)[1]
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Dosage:0.01 mg/kg; 0.1 mg/kg
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Administration:s.c.; single dose
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Result:Produced mean reentry latencies statistically greater than dizocilpine alone.
Demonstrated a statistically significant overall treatment effect.
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Animal Model:Charles River CF-1 (male, 25-30 g)[1]
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Dosage:10 mg/kg; 100 mg/kg
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Administration:s.c.; single dose
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Result:Produced statistically significant increases in mean escape jump latencies compared to vehicle-treated animals.
Chemical Information
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No. CAS 25451-53-0
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Peso molecular 195.22
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Fòrmula C10H13NO3
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SMILES
O=C(N)OCC(CO)C1=CC=CC=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SCH 54388 Related Classifications
HY-123280 Related Classifications
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